Cali
| Origin | Destination | Departure | Arrival |
| Cali | Popayan | 01:00 | 01:04 |
| Cali | Pasto | 01:00 | 01:08 |
| Cali | Manizales | 04:30 | 04:35 |
| Cali | Armenia | 04:30 | 04:33 |
| Cali | Pasto | 05:15 | 05:26 |
| Cali | Popayan | 05:30 | 05:33 |
| Cali | Buga | 06:00 | 06:01 |
| Cali | Buga | 06:15 | 06:16 |
| Cali | Popayan | 07:00 | 07:03 |
| Cali | Bogota | 07:30 | 07:41 |
| Cali | Popayan | 08:00 | 08:03 |
| Cali | Pereira | 08:30 | 08:33 |
| Cali | Popayan | 09:00 | 09:04 |
| Cali | Cucuta | 09:00 | 09:23 |
| Cali | Pasto | 09:00 | 09:08 |
| Cali | Cucuta | 10:00 | 10:26 |
| Cali | Popayan | 10:30 | 10:32 |
| Cali | Ibague | 12:30 | 12:37 |
| Cali | Florencia | 12:30 | 12:46 |
| Cali | Neiva | 12:30 | 12:41 |
| Cali | Armenia | 12:30 | 12:34 |
| Cali | Bogota | 13:00 | 13:11 |
| Cali | Barranquilla | 13:00 | 13:24 |
| Cali | Popayan | 13:00 | 13:03 |
| Cali | Pereira | 13:30 | 13:33 |
| Cali | Pereira | 14:00 | 14:03 |
| Cali | Manizales | 14:30 | 14:34 |
| Cali | Tumaco | 16:30 | 16:46 |
| Cali | Pereira | 17:00 | 17:03 |
| Cali | Cartagena | 18:00 | 18:28 |
| Cali | Pasto | 19:00 | 19:09 |
| Cali | Ipiales | 19:00 | 19:11 |
| Cali | Popayan | 19:00 | 19:03 |
| Cali | Armenia | 19:00 | 19:03 |
| Cali | Bogota | 20:00 | 20:12 |
| Cali | Pasto | 20:15 | 20:24 |
| Cali | Ipiales | 20:15 | 20:27 |
| Cali | Florencia | 20:30 | 20:42 |
| Cali | Neiva | 20:30 | 20:36 |
| Cali | Ibague | 20:45 | 20:52 |
| Cali | Popayan | 21:00 | 21:04 |
| Cali | Bogota | 21:30 | 21:42 |
| Cali | Pasto | 21:45 | 21:54 |
| Cali | Ipiales | 21:45 | 21:57 |
| Cali | Ipiales | 22:00 | 22:12 |
| Type | Name | km |
| bus | Terminal de Transporte Cali | 0.0 |
| bus | Cali Terminal | 0.0 |
| bus | Coomotor Cali | 0.0 |
| van | Terminal de Transporte Cali | 0.1 |
| bus | Cali Bus Terminal Cl 30 Nte | 0.1 |